Rabbit Secondary Antibodies
Innovative Research Inc Dog IgM Kit
Canine Interleukin-1 Beta (IL-1b) Recombinant 5ug - has been recombinantly produced in yeast and purified using ion-exchange chromatography. This is a loyphilized powder with a purity of greater than 95% as determined by SDS-PAGE analysis. This product is endotoxin free, naturally folded, and pos-translationally modified. It can be used in cell culture, as an ELISA Standard for IL-1b, and as a Western Blot control. IL-1b is syntheszied as a precursor form protein following stimulation of innate immune cells by Toll-like receptors or RIG-like receptors. The IL-1b precursor needs to be cleaved by caspase-1 in order to induce binding abilities, and caspase needs to be activated by the inflammasome (mediated by sytoplasmic pattern recognition receptor signaling). As a result, the secretion of IL-1b is dependent on the necessary steps and activation of the appropriate receptors in order to become active itself.
ABclonal Technology ANT2/SLC25A5 Rabbit mAb
This gene is a member of the mitochondrial carrier subfamily of solute carrier protein genes The product of this gene functions as a gated pore that translocates ADP from the cytoplasm into the mitochondrial matrix and ATP from the mitochondrial matrix into the cytoplasm The protein forms a homodimer embedded in the inner mitochondria membrane Suppressed expression of this gene has been shown to induce apoptosis and inhibit tumor growth The human genome contains several non-transcribed pseudogenes of this gene
Cell Signaling Technology DNMT3A D23G1 Rabbit mAb BSA and Azide Free 100 ug
DNMT3A D23G1 Rabbit mAb BSA and Azide Free 100 ug
ABclonal Technology Pepsinogen II PG II Rabbit mAb
This gene encodes an aspartic proteinase that belongs to the peptidase family A1 The encoded protein is a digestive enzyme that is produced in the stomach and constitutes a major component of the gastric mucosa This protein is also secreted into the serum This protein is synthesized as an inactive zymogen that includes a highly basic prosegment This enzyme is converted into its active mature form at low pH by sequential cleavage of the prosegment that is carried out by the enzyme itself Polymorphisms in this gene are associated with susceptibility to gastric cancers Serum levels of this enzyme are used as a biomarker for certain gastric diseases including Helicobacter pylori related gastritis Alternate splicing results in multiple transcript variants A pseudogene of this gene is found on chromosome 1
Cayman Chemical Pax5CTerm RabbIt Monclon 100uL
A RIPK2 inhibitor inhibits RIPK2 by 65 in a kinase assay at 10 UM inhibits VEGFR3 by greater than 90 as well as 14 additional kinases by 60-89 in a panel of 344 kinases at 10 UM reduces colonic damage in a mouse model of TNBS-induced colitis at 7.5 and 145 mg/kg twice per day a prodrug
ABclonal Technology CD45RB Rabbit mAb
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth differentiation mitosis and oncogenic transformation This PTP contains an extracellular domain a single transmembrane segment and two tandem intracytoplasmic catalytic domains and thus is classified as a receptor type PTP This PTP has been shown to be an essential regulator of T- and B-cell antigen receptor signaling It functions through either direct interaction with components of the antigen receptor complexes or by activating various Src family kinases required for the antigen receptor signaling This PTP also suppresses JAK kinases and thus functions as a regulator of cytokine receptor signaling Alternatively spliced transcripts variants of this gene which encode distinct isoforms have been reported
![REVMAB BIOSCIENCES USA INC IgG2b Rabbit Anti-Mouse Monoclonal Antibody [RM108]](https://assets.fishersci.com/TFS-Assets/CCG/product-images/VN00138964-31100400-IGG2B-ELISA.PNG-250.jpg)
REVMAB BIOSCIENCES USA INC IgG2b Rabbit Anti-Mouse Monoclonal Antibody [RM108]
Anti-Mouse IgG2b rabbit monoclonal antibody, Clone RM108 (100UG) ; WB (stronger on nonreduced), IP, ICC, IHC, FC, ELISA validated; Product info: www.revmab.com
ABclonal Technology CD99 Rabbit mAb
The protein encoded by this gene is a cell surface glycoprotein involved in leukocyte migration T-cell adhesion ganglioside GM1 and transmembrane protein transport and T-cell death by a caspase-independent pathway In addition the encoded protein may have the ability to rearrange the actin cytoskeleton and may also act as an oncosuppressor in osteosarcoma This gene is found in the pseudoautosomal region of chromosomes X and Y and escapes X-chromosome inactivation There is a related pseudogene located immediately adjacent to this locus
ABclonal Technology BOK Rabbit mAb
The protein encoded by this gene belongs to the BCL2 family members of which form homo- or heterodimers and act as anti- or proapoptotic regulators that are involved in a wide variety of cellular processes Studies in rat show that this protein has restricted expression in reproductive tissues interacts strongly with some antiapoptotic BCL2 proteins not at all with proapoptotic BCL2 proteins and induces apoptosis in transfected cells Thus this protein represents a proapoptotic member of the BCL2 family
Cayman Chemical p16INK4ACTerm RabbIt Mon 100uL
A derivative of DL-homocysteine inhibits the growth of B. campestris L. sativa and E. utilis roots at 50 UM decreases the maximum rate of left ventricular developed pressure systolic left ventricular pressure and coronary flow in isolated rat hearts at 10 UM induces arteriosclerotic plaque formation in rabbits at 30 mg/kg for eight weeks has also been used as a precursor in the synthesis of thiolactone-containing monomers for use in polymer-based formaldehyde-scavenging coatings